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Found 4 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM50574401'
TargetEstrogen receptor(Homo sapiens (Human))
X-Chem

Curated by ChEMBL
LigandPNGBDBM50574401(CHEMBL4855559)
Affinity DataIC50:  7.20nMAssay Description:Binding affinity to ERalpha D538G mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
X-Chem

Curated by ChEMBL
LigandPNGBDBM50574401(CHEMBL4855559)
Affinity DataIC50:  8.10nMAssay Description:Binding affinity to ERalpha Y537S mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
X-Chem

Curated by ChEMBL
LigandPNGBDBM50574401(CHEMBL4855559)
Affinity DataIC50:  15nMAssay Description:Binding affinity to recombinant His-tagged ERalpha LBD (307 to 554 residue) (unknown origin) expressed in Escherichia coli preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
X-Chem

Curated by ChEMBL
LigandPNGBDBM50574401(CHEMBL4855559)
Affinity DataIC50:  21nMAssay Description:Binding affinity to ERalpha S463P mutant (unknown origin) expressed in Escherichia coli preincubated for 15 mins followed by ligand addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed