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Report error Found 5 Enz. Inhib. hit(s) with Target = 'Eukaryotic initiation factor 4A-I' and Ligand = 'BDBM50610942'
TargetEukaryotic initiation factor 4A-I(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50610942(CHEMBL5267864)
Affinity DataKi:  9.59E+3nMAssay Description:Competitive inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using 250 uM ATP and vary...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEukaryotic initiation factor 4A-I(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50610942(CHEMBL5267864)
Affinity DataKi:  1.03E+4nMAssay Description:Uncompetitive inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using varying concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEukaryotic initiation factor 4A-I(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50610942(CHEMBL5267864)
Affinity DataIC50:  2.66E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEukaryotic initiation factor 4A-I(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50610942(CHEMBL5267864)
Affinity DataIC50:  2.87E+4nMAssay Description:Inhibition of helicase activity of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using Cy3-labele...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEukaryotic initiation factor 4A-I(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50610942(CHEMBL5267864)
Affinity DataIC50:  1.61E+5nMAssay Description:Displacement of FAM-A-[CAA]5 from human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells preincubated with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed