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Found 12 Enz. Inhib. hit(s) with Target = 'Eukaryotic initiation factor 4A-I' and Ligand = 'BDBM50610969'
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))TBA
LigandPNGBDBM50610969(CHEMBL5278302)
Affinity DataKi:  4.27E+3nMAssay Description:Competitive inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using 250 uM ATP and vary...More data for this Ligand-Target Pair
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TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))TBA
LigandPNGBDBM50610969(CHEMBL5278302)
Affinity DataKi:  4.79E+3nMAssay Description:Uncompetitive inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using varying concentra...More data for this Ligand-Target Pair
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TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))TBA
LigandPNGBDBM50610969(CHEMBL5278302)
Affinity DataIC50:  6.58E+3nMAssay Description:Inhibition of helicase activity of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using Cy3-labele...More data for this Ligand-Target Pair
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TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))TBA
LigandPNGBDBM50610969(CHEMBL5278302)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA as substrate ...More data for this Ligand-Target Pair
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TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))TBA
LigandPNGBDBM50610969(CHEMBL5278302)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A R311K mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
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TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))TBA
LigandPNGBDBM50610969(CHEMBL5278302)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A R311E mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
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TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))TBA
LigandPNGBDBM50610969(CHEMBL5278302)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A T158V mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
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TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))TBA
LigandPNGBDBM50610969(CHEMBL5278302)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A T158A mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))TBA
LigandPNGBDBM50610969(CHEMBL5278302)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A R110M mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
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TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))TBA
LigandPNGBDBM50610969(CHEMBL5278302)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A R110L mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
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TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))TBA
LigandPNGBDBM50610969(CHEMBL5278302)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged eIF4A R110E mutant expressed in Escherichia coli BL21 CodonPlus cells using ATP and yeast RNA ...More data for this Ligand-Target Pair
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TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))TBA
LigandPNGBDBM50610969(CHEMBL5278302)
Affinity DataIC50:  5.83E+4nMAssay Description:Displacement of FAM-A-[CAA]5 from human recombinant N-terminal His6-tagged eIF4A expressed in Escherichia coli BL21 CodonPlus cells preincubated with...More data for this Ligand-Target Pair
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