Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Frizzled-7' and Ligand = 'BDBM50519308'
TargetFrizzled-7(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM50519308(CHEMBL4554351)
Affinity DataIC50:  32nMAssay Description:Inhibition of Frizzled-7 in HEK293 cells expressing Wnt assessed as reduction in Wnt signaling by firefly luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetFrizzled-7(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM50519308(CHEMBL4554351)
Affinity DataKd:  5.60nMAssay Description:Binding affinity to recombinant human Frizzled-7 (Gln33 to Leu185 residues)/human IgG1 chimeric protein expressed in CHO cells assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetFrizzled-7(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM50519308(CHEMBL4554351)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to recombinant human Frizzled-7 (Gln33 to Leu185 residues)/human IgG1 chimeric protein expressed in CHO cells by SPR assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed