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Found 5 Enz. Inhib. hit(s) with Target = 'G-protein coupled bile acid receptor 1' and Ligand = 'BDBM50399965'
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399965(CHEMBL2181246)
Affinity DataEC50:  10nMAssay Description:Agonist activity at TGR5 (unknown origin)More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399965(CHEMBL2181246)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399965(CHEMBL2181246)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human TGR5More data for this Ligand-Target Pair
LigandPNGBDBM50399965(CHEMBL2181246)
Affinity DataEC50:  2.56E+3nMAssay Description:Agonist activity at mouse TGR5More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399965(CHEMBL2181246)
Affinity DataEC50:  10nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cellsMore data for this Ligand-Target Pair