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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM486054'
TargetGenome polyprotein(HCV)
Cocrystal Pharma

US Patent
LigandPNGBDBM486054(US10947210, Compound 06-6A | US10947210, Compound ...)
Affinity DataIC50:  550nMAssay Description:The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetGenome polyprotein(HCV)
Cocrystal Pharma

US Patent
LigandPNGBDBM486054(US10947210, Compound 06-6A | US10947210, Compound ...)
Affinity DataIC50:  550nMAssay Description:The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetGenome polyprotein(HCV)
Cocrystal Pharma

US Patent
LigandPNGBDBM486054(US10947210, Compound 06-6A | US10947210, Compound ...)
Affinity DataEC50: <100nMAssay Description:HCV replicon assay is based on the luciferase reporter cell line (Huh-luc/neo-ET). This reporter cell line is a human liver carcinoma cell line (Huh-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent