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Found 3 Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial' and Ligand = 'BDBM108454'
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108454(US8604016, 11 | US9938267, Cmpd ID 11)
Affinity DataIC50:  380nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108454(US8604016, 11 | US9938267, Cmpd ID 11)
Affinity DataIC50:  1.40E+3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108454(US8604016, 11 | US9938267, Cmpd ID 11)
Affinity DataIC50:  1.40E+3nMAssay Description:No preinc (Column 4).More data for this Ligand-Target Pair
In DepthDetails US Patent