Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial' and Ligand = 'BDBM108512'
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108512(US8604016, 72 | US9938267, Cmpd ID 72)
Affinity DataIC50:  202nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108512(US8604016, 72 | US9938267, Cmpd ID 72)
Affinity DataIC50:  590nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108512(US8604016, 72 | US9938267, Cmpd ID 72)
Affinity DataIC50:  590nMAssay Description:No preinc (Column 4).More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM108512(US8604016, 72 | US9938267, Cmpd ID 72)
Affinity DataIC50:  2.30E+3nMAssay Description:Allosteric inhibition of human kidney glutaminase using [3H]-Glutamine as substrate in presence of inhibitor incubated for 45 mins by Perkin Elmer ba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed