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Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM251575'
Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM251575
(US9452998, Table 4 Compound 5)
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Affinity Data
IC50: 0.200nM
pH: 7.0 T: 2°C
Assay Description:
Types of GSK-3 assay used to test the selectivity/off target potential compounds of the invention with respect to PKC α/θ inhibition activity inclu...
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Ligand Info
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