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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM50397747'
TargetGlycogen synthase kinase-3 beta(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50397747(CHEMBL2177157)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant GSK3beta using biotin- AAEELDSRAGS(PO3H2)PQL as substrate and [gamma32P]ATP after 20 mins by scintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50397747(CHEMBL2177157)
Affinity DataIC50:  49nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed