Found 4 Enz. Inhib. hit(s) with Target = 'Glycylpeptide N-tetradecanoyltransferase' and Ligand = 'BDBM50364113' TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Inhibition of N-terminal TEV cleavage site-fused His6 tagged Leishmania major NMT (11 to 421 residues) expressed in Escherichia coli Rosetta-2 cells ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of Leishmania major NMT H398N mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:Inhibition of Leishmania major NMT L421Q mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Leishmania major N-myristoyltransferase using [3H]myristoyl-CoA and GCGGSKVKPQPPQAK(biotin)-amide as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
