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Found 3 Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM50142026'
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50142026(3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3...)
Affinity DataIC50:  2nMAssay Description:Inhibition of receptor Tyrosine kinase A, TrkA (nerve growth factor receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50142026(3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3...)
Affinity DataIC50:  2nMAssay Description:Inhibition of GST-fused TrkA (unknown origin) expressed in SF9 cells using H2N-RRRAAAEEIYGEINH2 peptide as substrate preincubated with ATP and Mg and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50142026(3-((1-methyl-1H-indol-3-yl)methylene)-1H-pyrrolo[3...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human N- terminal GST-tagged TrkA cytoplasmic domain (436 to 790 residues) expressed in baculovirus infected sf21 cells using biotinyla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed