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Found 4 Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50297366'
TargetHistamine H3 receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297366(4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-biphen...)
Affinity DataKi:  1nMAssay Description:Inverse agonist activity against human histamine H3 receptor by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297366(4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-biphen...)
Affinity DataKi:  4.57nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297366(4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-biphen...)
Affinity DataKi:  4.57nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297366(4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-biphen...)
Affinity DataKi:  8nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed