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Found 4 Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50538681'
TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538681(CHEMBL4595327)
Affinity DataKi:  12nMAssay Description:Inhibition of UR-DEBa242 binding to human recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538681(CHEMBL4595327)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-histamine from Galphai2/Gbeta1gamma2-coupled human recombinant H4R expressed in baculovirus infected Sf9 insect cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538681(CHEMBL4595327)
Affinity DataKi:  31nMAssay Description:Inhibition of UR-DEBa242 binding to mouse recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538681(CHEMBL4595327)
Affinity DataEC50:  50nMAssay Description:Agonist activity at mouse recombinant H4R expressed in HEK293T cells by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed