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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50555464'
TargetHistone deacetylase 1(Homo sapiens (Human))
A*Star

Curated by ChEMBL
LigandPNGBDBM50555464(CHEMBL4744689)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
A*Star

Curated by ChEMBL
LigandPNGBDBM50555464(CHEMBL4744689)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate measured after 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed