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Found 6 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM50519457'
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50519457(CHEMBL4452620)
Affinity DataKi:  35nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in baculovirus infected Sf9 cells assessed as inhibitory constant using FAM-RHKK-Ac as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50519457(CHEMBL4452620)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 5 hrs by e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50519457(CHEMBL4452620)
Affinity DataIC50:  24nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50519457(CHEMBL4452620)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Danio rerio)
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50519457(CHEMBL4452620)
Affinity DataIC50:  269nMAssay Description:Inhibition of N-terminal 6 His-SUMO tagged Zebrafish HDAC6 CD2 domain expressed in Escherichia coli BL21(DE3) RILP pretreated for 10 mins before FITC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50519457(CHEMBL4452620)
Affinity DataIC50:  580nMAssay Description:Inhibition of HDAC6 in human HeLa cells incubated for 15 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed