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Found 3 Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1' and Ligand = 'BDBM50552745'
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552745(CHEMBL4792037 | US20240067660, Compound 25)
Affinity DataKi:  0.200nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552745(CHEMBL4792037 | US20240067660, Compound 25)
Affinity DataKi:  0.210nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM50552745(CHEMBL4792037 | US20240067660, Compound 25)
Affinity DataKi:  0.210nMAssay Description:Inhibition of Terbium-labeled BIM BH3 peptide binding to MCL1 (unknown origin) incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed