Found 11 Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor 1 receptor' and Ligand = 'BDBM50315887' TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Piramal Enterprises
Curated by ChEMBL
Piramal Enterprises
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of IGF1R (unknown origin) using poly-G1 as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by time-resolve...More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Piramal Enterprises
Curated by ChEMBL
Piramal Enterprises
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length IGF-1 receptor (unknown origin) autophosphorylation transfected in HEK293 cells pretreated for 60 mins followed by IGF-1 st...More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Piramal Enterprises
Curated by ChEMBL
Piramal Enterprises
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of full length IGF-1 receptor (unknown origin) transfected in Ba/F3 cells assessed as cell proliferationMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Piramal Enterprises
Curated by ChEMBL
Piramal Enterprises
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of GST-tagged IGF-1R catalytic domain (unknown origin) using omnia Y peptide-12 as substrate assessed as inhibition of substrate phosphory...More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Piramal Enterprises
Curated by ChEMBL
Piramal Enterprises
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of GST-tagged IGF-1R catalytic domain (unknown origin) using omnia Y peptide-12 as substrate assessed as inhibition of substrate phosphory...More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Piramal Enterprises
Curated by ChEMBL
Piramal Enterprises
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of IGF-1 receptor (unknown origin) in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Piramal Enterprises
Curated by ChEMBL
Piramal Enterprises
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant IGF1R expressed in Sf21 cells by time resolved fluorescence assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Piramal Enterprises
Curated by ChEMBL
Piramal Enterprises
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Piramal Enterprises
Curated by ChEMBL
Piramal Enterprises
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human IGF1R expressed in mouse 3T3 cells by ELISA based assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Piramal Enterprises
Curated by ChEMBL
Piramal Enterprises
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Compound was tested for the biological activity at the Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Piramal Enterprises
Curated by ChEMBL
Piramal Enterprises
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant IGF-1R assessed as inhibition in the presence of ATP at 100 uM/l by ELISA methodMore data for this Ligand-Target Pair
