Report error Found 7 Enz. Inhib. hit(s) with Target = 'Integrase' and Ligand = 'BDBM50123468'
Affinity DataIC50: 10nMAssay Description:Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against integrase-catalysed strand transferMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
Fondazione Cenci Bolognettiuniversit£
Curated by ChEMBL
Fondazione Cenci Bolognettiuniversit£
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity by high throughput electrochemiluminescent assay in presence of magnesiumMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
Fondazione Cenci Bolognettiuniversit£
Curated by ChEMBL
Fondazione Cenci Bolognettiuniversit£
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Potency of compound was tested against HIV-1- containing integrase mutations (NL4-3)More data for this Ligand-Target Pair
Affinity DataEC50: >800nMAssay Description:Potency of compound was tested against HIV-1- containing integrase mutations (T66I, S153Y)More data for this Ligand-Target Pair