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Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50055900'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055900(3-{2-[(R)-3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-i...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of ADP-induced platelet aggregation in human platelet rich plasma (hPRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055900(3-{2-[(R)-3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-i...)
Affinity DataIC50:  140nMAssay Description:Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055900(3-{2-[(R)-3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-i...)
Affinity DataIC50:  240nMAssay Description:Inhibition of platelet aggregation in human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055900(3-{2-[(R)-3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-i...)
Affinity DataIC50:  860nMAssay Description:Inhibition of human platelet aggregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed