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Found 3 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50062781'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062781(((S)-1-{2-[4-(2-Amino-ethyl)-benzoylamino]-acetyl}...)
Affinity DataIC50:  2.5nMAssay Description:Ability to inhibit binding of biotin-labeled human fibrinogen to immobilized fibrinogen receptor purified from human erythroleukemia(HEL) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062781(((S)-1-{2-[4-(2-Amino-ethyl)-benzoylamino]-acetyl}...)
Affinity DataIC50:  130nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of human platelets by 50% in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062781(((S)-1-{2-[4-(2-Amino-ethyl)-benzoylamino]-acetyl}...)
Affinity DataIC50:  230nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of guinea pig platelets by 50% in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed