Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50062790'
TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062790(((S)-4-Carboxymethyl-1-{2-[(4-guanidinomethyl-cycl...)
Affinity DataIC50:  20nMAssay Description:Ability to inhibit binding of biotin-labeled human fibrinogen to immobilized fibrinogen receptor purified from human erythroleukemia(HEL) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062790(((S)-4-Carboxymethyl-1-{2-[(4-guanidinomethyl-cycl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of human platelets by 50% in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50062790(((S)-4-Carboxymethyl-1-{2-[(4-guanidinomethyl-cycl...)
Affinity DataIC50:  4.20E+3nMAssay Description:Concentration required to inhibit adenosine diphosphate (ADP) induced aggregation of guinea pig platelets by 50% in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed