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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM278838'
Target
Interleukin-1 receptor-associated kinase 4
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM278838
(N-(3-chloro-1-methyl- 1H-pyrazol-4-yl)-2- [(1S,4S)...)
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Affinity Data
IC50: 15nM
pH: 7.2
Assay Description:
The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...
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Target Info
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Ligand Info
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