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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM50547948'
TargetInterleukin-1 receptor-associated kinase 4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50547948(CHEMBL4742305)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50547948(CHEMBL4742305)
Affinity DataIC50:  103nMAssay Description:Inhibition of IRAK4 in human THP-1 cells assessed as inhibition of LTA-induced TNF-alpha production preincubated for 60 mins followed by LTA stimulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed