Found 1 Enz. Inhib. hit(s) with Target = 'Isoform APP695 of Amyloid-beta precursor protein [K595N,M596L]' and Ligand = 'BDBM571404'
TargetIsoform APP695 of Amyloid-beta precursor protein [K595N,M596L](Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataEC50: 14nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair