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Found
1
Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 2B' and Ligand = 'BDBM345366'
Target
Lysine-specific demethylase 2B
(Homo sapiens (Human))
Genentech
US Patent
Ligand
BDBM345366
(1-cyclobutyl-4-(1-((4-isopropylphenyl)sulfonyl)-4,...)
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Affinity Data
IC50: 0.0430nM
Assay Description:
Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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