Report error Found 5 Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM17750'
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 24nMpH: 7.5 T: 22°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) was incubated with compound in reaction buffer. Control reactions were run in each plate. ...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cellsMore data for this Ligand-Target Pair