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Found 4 Enz. Inhib. hit(s) with Target = 'Macrophage migration inhibitory factor' and Ligand = 'BDBM50206083'
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50206083(CHEMBL3927658 | US10968198, Example 43)
Affinity DataKi:  34nMAssay Description:Data obtained for the Example compounds, obtained using the methods described in Example B.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50206083(CHEMBL3927658 | US10968198, Example 43)
Affinity DataKi:  39nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50206083(CHEMBL3927658 | US10968198, Example 43)
Affinity DataKi:  39nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yale University

US Patent
LigandPNGBDBM50206083(CHEMBL3927658 | US10968198, Example 43)
Affinity DataKd:  63nMAssay Description:Inhibition of recombinant human MIF tautomerase activity assessed as decrease in formation of borate complex of enol product using 4-HPP as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed