Report error Found 15 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM17657'
Affinity DataKi: 390nMAssay Description:Binding affinity to mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.16E+3nMAssay Description:Displacement of [3H]Quisqualate from human mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rat)
Case Western Reserve University
Curated by PDSP Ki Database
Case Western Reserve University
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 5(Rat)
Case Western Reserve University
Curated by PDSP Ki Database
Case Western Reserve University
Curated by PDSP Ki Database
Affinity DataKi: 1.14E+4nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rat)
Case Western Reserve University
Curated by PDSP Ki Database
Case Western Reserve University
Curated by PDSP Ki Database
Affinity DataEC50: 8.99E+3nMAssay Description:Agonist activity at rat mGlu5 receptor expressed in HEK293 cells assessed as IP1 accumulation by IP-One functional assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rat)
Case Western Reserve University
Curated by PDSP Ki Database
Case Western Reserve University
Curated by PDSP Ki Database
Affinity DataEC50: 8.00E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5b in ratMore data for this Ligand-Target Pair
Affinity DataEC50: 4.10E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in humanMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rat)
Case Western Reserve University
Curated by PDSP Ki Database
Case Western Reserve University
Curated by PDSP Ki Database
Affinity DataEC50: 4.70E+3nMAssay Description:Agonist activity at rat mGlu5 receptor expressed in HEK293 cells by intracellular Ca2+ mobilization assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rat)
Case Western Reserve University
Curated by PDSP Ki Database
Case Western Reserve University
Curated by PDSP Ki Database
Affinity DataEC50: 4.68E+3nMAssay Description:Agonist activity at rat mGlu5 receptor expressed in HEK293 cells by intracellular Ca2+ mobilization assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rat)
Case Western Reserve University
Curated by PDSP Ki Database
Case Western Reserve University
Curated by PDSP Ki Database
Affinity DataEC50: 1.20E+3nMAssay Description:Activity at rat recombinant mGluR5 expressed in CHO cells assessed as intracellular calcium concentrationMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rat)
Case Western Reserve University
Curated by PDSP Ki Database
Case Western Reserve University
Curated by PDSP Ki Database
Affinity DataEC50: 1.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in ratMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+4nMAssay Description:Agonist activity at mGlu5 receptor (unknown origin) expressed in CHO cells assessed as increase in Gq-mediated PI hydrolysis after 45 mins by yttrium...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rat)
Case Western Reserve University
Curated by PDSP Ki Database
Case Western Reserve University
Curated by PDSP Ki Database
Affinity DataEC50: 1.20E+3nMAssay Description:Activity at rat mGluR5 by measuring intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair