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Affinity DataKi: 440nMAssay Description:Negative allosteric modulation at rat mGluR5 receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Displacement of [3H]3-methoxy-5-(2-pyridinylethynyl) pyridine from mGluR5 allosteric siteMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Positive allosteric modulation of mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Negative allosteric modulation at rat mGluR5 receptorMore data for this Ligand-Target Pair
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