Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50402787' TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-methoxyPEPy from rat mGlu5 receptor expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 398nMAssay Description:Ago-positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells by fluorescence-based calcium flux assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 4.50E+3nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells by fluorescence-based calcium flux assayMore data for this Ligand-Target Pair
