Found 7 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 10' and Ligand = 'BDBM86632' TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of JNK3 (unknown origin) after 1 hr incubationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataIC50: 0.75nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataIC50: 0.75nMAssay Description:Inhibition of wild-type human partial length JNK3 (V28 to Q422 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataIC50: 0.75nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of JNK3-mediated c-jun phosphorylation in human HeLa cells after 1 hr incubationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataIC50: 244nMAssay Description:Inhibition of JNK3-mediated c-jun phosphorylation in human A375 cells after 1 hr incubationMore data for this Ligand-Target Pair
