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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 14' and Ligand = 'BDBM552835'
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552835((R)-7-(3-(2-(5H-Pyrrolo[2,3-b]pyrazin-7-yl-6-d)thi...)
Affinity DataIC50: <100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreenŽ (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552835((R)-7-(3-(2-(5H-Pyrrolo[2,3-b]pyrazin-7-yl-6-d)thi...)
Affinity DataIC50: <100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreenŽ (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed