Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 1' and Ligand = 'BDBM459443'
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM459443(US10752635, Example 4, Peak 1 | US11492354, Exampl...)
Affinity DataKi:  1nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM459443(US10752635, Example 4, Peak 1 | US11492354, Exampl...)
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM459443(US10752635, Example 4, Peak 1 | US11492354, Exampl...)
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM459443(US10752635, Example 4, Peak 1 | US11492354, Exampl...)
Affinity DataKi:  105nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed