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Found 5 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50376594'
TargetMu-type opioid receptor(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50376594(CHEMBL260120)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]diprenorphine from human MOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50376594(CHEMBL260120)
Affinity DataIC50:  28nMAssay Description:Displacement of [3H]naloxone from MOR in rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50376594(CHEMBL260120)
Affinity DataIC50:  2.20E+4nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50376594(CHEMBL260120)
Affinity DataIC50:  2.81E+4nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50376594(CHEMBL260120)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human MOR expressed in HEK293 cell membrane assessed as inhibition of forskolin-induced cAMP accumulation by by liquid scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed