Found 2 Enz. Inhib. hit(s) with Target = 'NACHT, LRR and PYD domains-containing protein 3' and Ligand = 'BDBM50605172' TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
School Of Pharmacy Anhui Medical University
Curated by ChEMBL
School Of Pharmacy Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated C57BL/6 mouse bone marrow-derived macrophages assessed as reduction in IL-1beta ...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
School Of Pharmacy Anhui Medical University
Curated by ChEMBL
School Of Pharmacy Anhui Medical University
Curated by ChEMBL
Affinity DataKd: 213nMAssay Description:Binding affinity to GFP-fused NLRP3 (unknown origin) expressed in HEK293T cells by MST assayMore data for this Ligand-Target Pair
