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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-4' and Ligand = 'BDBM141884'
LigandPNGBDBM141884(US8921410, Table 2 Compound 19)
Affinity DataKi:  12nM ΔG°:  -44.6kJ/moleT: 21°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
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TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandPNGBDBM141884(US8921410, Table 2 Compound 19)
Affinity DataKi:  35nM ΔG°:  -42.0kJ/moleT: 21°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent