Found 2 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50259921'
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells co-expressing human RIC-3 assessed as area under current curve at holding potential of...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataEC50: 35nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair