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Found 3 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50369323'
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50369323(MECAMYLAMINE)
Affinity DataIC50:  1.80E+3nMAssay Description:Ability to block activation of acetylcholine-stimulated currents in human alpha-7 homomers expressed in oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50369323(MECAMYLAMINE)
Affinity DataIC50:  2.20E+3nMAssay Description:Antagonist activity at human alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50369323(MECAMYLAMINE)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibitory concentration against Nicotinic acetylcholine receptor alpha 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed