Found 6 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50530216' TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Florence
Curated by ChEMBL
University of Florence
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7* nAChR in rat brain P2 membranes after 2.5 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Florence
Curated by ChEMBL
University of Florence
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7* nAChR in rat brain P2 membranes after 2.5 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Florence
Curated by ChEMBL
University of Florence
Curated by ChEMBL
Affinity DataEC50: 2.71E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of Florence
Curated by ChEMBL
University of Florence
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Agonist activity at human alpha7 nAChR expressed in mouse Neuro2a cells co-expressing chaperone NACHO assessed as increase in intracellular Ca2+ leve...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University of Florence
Curated by ChEMBL
University of Florence
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Agonist activity at human alpha7 nAChR expressed in mouse Neuro2a cells co-expressing chaperone NACHO assessed as increase in intracellular Ca2+ leve...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Florence
Curated by ChEMBL
University of Florence
Curated by ChEMBL
Affinity DataEC50: 2.71E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
