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Report error Found 5 Enz. Inhib. hit(s) with Target = 'Neurotensin receptor type 1' and Ligand = 'BDBM50440738'
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440738(CHEMBL2431105)
Affinity DataIC50:  0.240nMAssay Description:Displacement of [125I]-neurotensin from NTR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440738(CHEMBL2431105)
Affinity DataIC50:  0.240nMAssay Description:Displacement of [125I]-neurotensin from NTR1 in HUVEC after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440738(CHEMBL2431105)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at NTR1 (unknown origin) expressed in human U2OS cells coexpressing beta-arrestin assessed as inhibition of ML314-induced effect ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440738(CHEMBL2431105)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at NTR1 (unknown origin) expressed in human U2OS cells coexpressing beta-arrestin by GFP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeurotensin receptor type 1(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440738(CHEMBL2431105)
Affinity DataEC50: >8.00E+4nMAssay Description:Agonist activity at NTR1 in human U2OS cells after 1 hr by beta-arrestin GFP reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed