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Found 3 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50466378'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466378(CHEMBL4282063)
Affinity DataIC50: <30nMAssay Description:Displacement of [3H]-Digoxin from recombinant human GST-fused RORgammat LBD after 1 to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466378(CHEMBL4282063)
Affinity DataIC50:  180nMAssay Description:Transrepression of recombinant human GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Mus musculus)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466378(CHEMBL4282063)
Affinity DataIC50: >1.00E+4nMAssay Description:Transrepression of recombinant mouse GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed