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Found 3 Enz. Inhib. hit(s) with Target = 'Orexin/Hypocretin receptor type 1' and Ligand = 'BDBM102131'
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM102131(US8530648, 28)
Affinity DataKi:  288nMAssay Description:Antagonist activity at human OX1 receptor expressed in CHO cells assessed as inhibition of orexin A-induced Ca2+ accumulation after 1 hr by Fluo-4-AM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM102131(US8530648, 28)
Affinity DataKi:  314nMpH: 7.4Assay Description:FLIPR assay using orexin receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM102131(US8530648, 28)
Affinity DataKd:  374nMpH: 7.5Assay Description:Radioligand binding assay using orexin receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent