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Found 3 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM102131'
TargetOrexin receptor type 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM102131(US8530648, 28)
Affinity DataKi:  30nMpH: 7.4Assay Description:FLIPR assay using orexin receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM102131(US8530648, 28)
Affinity DataKi:  62nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK cells assessed as inhibition of orexin A-induced Ca2+ accumulation after 1 hr by Fluo-4-AM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM102131(US8530648, 28)
Affinity DataKd:  42nMpH: 7.5Assay Description:Radioligand binding assay using orexin receptor.More data for this Ligand-Target Pair
In DepthDetails US Patent