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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM47177'
TargetPlasma kallikrein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM47177(BDBM108100 | US8598206, Table 6, 9)
Affinity DataKi:  2nMAssay Description:The inhibitory effect for the individual enzymes was determined in analogy to a previously disclosed method (Stürzebecher et al., J. Med. Chem.,...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetPlasma kallikrein(Human)
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM47177(BDBM108100 | US8598206, Table 6, 9)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human t-PA was determined by the method described in [0092]-[0098] using recombinant human tissue-type plasminogen activator (Actilyse&...More data for this Ligand-Target Pair
In DepthDetails US Patent