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Found 4 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27712'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM27712(5-chloro-2-methyl-3,4-dihydroquinazolin-4-one | CH...)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of PARP1 using TACS-Sapphire substrate for 30 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM27712(5-chloro-2-methyl-3,4-dihydroquinazolin-4-one | CH...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM27712(5-chloro-2-methyl-3,4-dihydroquinazolin-4-one | CH...)
Affinity DataIC50:  1.20E+3nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM27712(5-chloro-2-methyl-3,4-dihydroquinazolin-4-one | CH...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed