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Found 2 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM318017'
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM318017(8-Methyl-2-[4-(1-pyrimidin-2-ylpropyl)piperazin-1-...)
Affinity DataIC50:  22nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM318017(8-Methyl-2-[4-(1-pyrimidin-2-ylpropyl)piperazin-1-...)
Affinity DataIC50:  24.7nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent