Found 3 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM50541694' TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
OSLO UNIVERSITETSSYKEHUS HF; FORSCHUNGSVERBUND BERLIN E.V.; UNIVERSITY OF OULU
US Patent
OSLO UNIVERSITETSSYKEHUS HF; FORSCHUNGSVERBUND BERLIN E.V.; UNIVERSITY OF OULU
US Patent
Affinity DataIC50: 2nMAssay Description:Biochemical IC50 values for the following compounds were determined in accordance with the following protocol (see also Anumala et al., Discovery of ...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
OSLO UNIVERSITETSSYKEHUS HF; FORSCHUNGSVERBUND BERLIN E.V.; UNIVERSITY OF OULU
US Patent
OSLO UNIVERSITETSSYKEHUS HF; FORSCHUNGSVERBUND BERLIN E.V.; UNIVERSITY OF OULU
US Patent
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human TNKS2 (873 to 1162 residues) measured after 20 hrs in presence of NAD+ by fluorescence assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
OSLO UNIVERSITETSSYKEHUS HF; FORSCHUNGSVERBUND BERLIN E.V.; UNIVERSITY OF OULU
US Patent
OSLO UNIVERSITETSSYKEHUS HF; FORSCHUNGSVERBUND BERLIN E.V.; UNIVERSITY OF OULU
US Patent
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
