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Found 2 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50006821'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006821(4-Methyl-N-[3-(quinolin-2-ylmethoxy)-benzoyl]-benz...)
Affinity DataIC50:  3.90E+3nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006821(4-Methyl-N-[3-(quinolin-2-ylmethoxy)-benzoyl]-benz...)
Affinity DataIC50:  6.20E+3nMAssay Description:Concentration that produces 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed