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Found 3 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50052022'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50052022((S)-2-[7-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-p...)
Affinity DataIC50:  47nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase translocation inhibitor in RBL-2H3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50052022((S)-2-[7-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-p...)
Affinity DataIC50:  100nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50052022((S)-2-[7-(Quinolin-2-ylmethoxy)-naphthalen-2-yl]-p...)
Affinity DataIC50:  800nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in human polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed